Atypia Meaning of Atypia: State of being not typical or normal. In medicine, atypia is an abnormality in cells in tissue. Also See: Magnesium Acupuncture Alzheimer Disease ALL Gluten Ancillary Test Arzoxifene hydrochloride Atorvastatin calcium Apoptosis Atypical teratoid/rhabdoid tumor ALSO SEE: Androgen