Appendage Meaning of Appendage In medicine, a body part (such as an arm or leg) that is attached to the main part of the body. Also See: Antioxidants Arctigenin Anaplastic Lymphoma Kinase Inhibitor Acalabrutinib Acute leukemia ABVE Arthralgia Adderall Adult-type fibrosarcoma ANS ALSO SEE: ATLL